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Tests for Coronavirus Vaccine Need This Ingredient: Horseshoe Crabs – The New York Times

Source: Tests for Coronavirus Vaccine Need This Ingredient: Horseshoe Crabs – The New York Times

Horseshoe Crab
Atlantic horseshoe crabs burrowing in the sand on Pickering Beach, a national horseshoe crab sanctuary near Little Creek, Del.Credit…Mike Segar/Reuters
  • June 3, 2020

For decades, drug companies have depended on a component in the blood of the horseshoe crab to test injectable medicines, including vaccines, for dangerous bacterial contaminants called endotoxins.

Conservationists and some businesses have pushed for wide acceptance of an alternative test, to protect the horseshoe crabs and birds that feed on their eggs. Earlier this year, these people seemed to be on the brink of success as the nongovernmental group that issues quality standards for such tests moved toward putting the alternative test on the same footing.

But on Friday, that organization, the U.S. Pharmacopeia, announced that the alternative test known as rFC (recombinant factor C) requires significantly more study.

Pharmacopeia representatives said they have 30 years of data on the current test and only two years on the new test so they needed more information.

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